Chronic Stress Could Be One of the Causes of Alzheimer’s


A group of scientists conducting research to understand the causes of Alzheimer’s have examined the link between chronic stress and Alzheimer’s. The study also includes examining many studies conducted in the past on this subject, and the results reveal the relationship between chronic stress and Alzheimer’s.

Alzheimer’s is a very common neurological disease for which there is still no definitive cure. The reason behind the lack of treatment for the disease is What is at the root of Alzheimer’s not yet fully understood.

Alzheimer’s may initially only affect skills such as thinking and remembering. In the future, it prevents patients from meeting their basic needs.. A lot of scientific research is being carried out for the best understanding of Alzheimer’s, which is extremely common and increasing in frequency, and for the development of treatments. Results Published in Biological Reviews If it’s a new job Examines the link between Alzheimer’s and chronic stress.

Chronic stress is one of the factors that feed Alzheimer’s:


Chronic stress is an important topic in research on Alzheimer’s and different studies have been conducted on this subject over the years. Especially childhood post-traumatic stress disorder that conditions such as these leave people ‘vulnerable’ for Alzheimer’s later in life. a research conducted Afterwards, scientists have now carried out a new research to better understand what the reason is.

The focus of the research is the hypothalamic-pituitary-adrenal axis, a pathway that connects the two parts of the brain with glands just above the lobes. (HPA axis) there is. This region, which plays a role in stress-related disorders and regulates the response to stress, has an important place in Alzheimer’s research.

One of the tasks of the HPA axis is, regulating the release of cortisol. The greater the stress, the more cortisol is released. Part of a class known as glucocorticoid hormones, this hormone raises blood sugar and suppresses the immune system.

Alzheimer's and chronic stress

Disruption of the HPA axis followed by increases in cortisol levels Often seen in Alzheimer’s cases and this makes the HPA axis an important region for understanding Alzheimer’s. However, scientists do not yet fully understand the reason for this increase.

In the research carried out, the researchers found that the genetic factors affecting the HPA axis, which are seen in diseases such as Alzheimer’s, contributes to neuron damage suggests that it may also affect the known inflammation in the brain. Molecular geneticist David Groth of Curtin University in Australia that chronic stress affects many biological pathways in our body. and states that the HPA axis is one of these ways. Groth, the relationship between Alzheimer’s and chronic stress “Genetic variations within these pathways can affect the way the brain’s immune system behaves, leading to a dysfunctional response. In the brain, this leads to a chronic disruption of normal brain processes, which then causes neurodegeneration and ultimately increases the risk of dementia‘ he sums it up.


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It is known that some symptoms of Alzheimer’s may begin to appear at an earlier age, and especially good understanding of possible causes whose effects can be measured, such as chronic stress, Prevention and treatment of Alzheimer’s thought to play an important role.

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